Juliane K. Strauss-Soukup, BS, PhD

Juliane K. Strauss-Soukup, BS, PhD
Professor
Vice Provost, Research and Scholarship
College of Arts and Sciences
Academic Appointments
Department
- Chemistry and Biochemistry
Position
- Professor
Teaching Activity
- Dr. Soukup teaches a wide selection of chemistry courses, including general chemistry, biochemistry, and nucleic acid biochemistry. She also mentors ~14 undergraduate research students each semester in independent research courses.
Biography
A more complete listing of scholarship, teaching, and research interests can be found in my Curriculum Vitae.
Publications and Presentations
Books
- , 120, 173-194
Articles
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Presentations
Research and Scholarship
Research and Scholarship Interests
- My laboratory is currently interested in studying the structure and function of a number of noncoding RNAs, specifically riboswitches, allosteric ribozymes and lncRNAs. One riboswitch project involves studying the structure and function of the bacterial glmS riboswitch that is also a ribozyme. We are interested in investigating whether non-natural riboswitch ligands can modulate gene expression and therefore may be able to act as antibiotics. Another project involves discovery of new riboswitches. One we are particularly interested in is a noncoding RNA found in mammals that is highly conserved among vertebrate genes required for spermine biosynthesis. The function of this mouse RNA element as a spermine riboswitch indicates a substantially broader distribution of riboswitches among eukaryotic organisms and represents a new drug target in a key metabolic process relevant to cellular and organism survival.
Current Research Projects
- In our work with noncoding RNAs we are currently designing a high-throughput system for studying non-natural riboswitch ligand analogs. In addition, we are collaborating with a lab on a SARS-CoV-2 project to investigate viral RNA-protein binding.
Grant Funding Received
- National Institutes of Health INBRE Program, "Nebraska Research Network in Functional Genomics"
- National Institutes of Health INBRE Program, “Understanding Genetic Regulation Through Structural Studies of Riboswitch-Metabolite Complexes”
- National Institutes of Health, renewal of “Antibiotic Properties of Artificial Agonists for a Bacterial Riboswitch”
- National Institutes of Health INBRE Program, "Nebraska Research Network in Functional Genomics"
- Gordon Research Conference PUI (Predominantly Undergraduate Institution) Award
- National Institutes of Health INBRE Program, supplement to "Nebraska Research Network in Functional Genomics", equipment and pilot project funding
- National Institutes of Health, ARRA competitive supplement to “Development of Artificial Agonists for a Bacterial Riboswitch”
- National Institutes of Health ARRA shared instrumentation grant, purchase of shared PhosphorImager Typhoon 9140,
- National Institutes of Health, “Development of Artificial Agonists for a Bacterial Riboswitch”
- Internal: Dr. George F. Haddix President’s Faculty Research Fund, Creighton University, “Using bacterial RNA switches as synthetic genetic devices”
- Internal: Dr. George F. Haddix President’s Faculty Research Fund, Creighton University, “Examination of spermine riboswitch function from different organisms for the development of antibiological agents”
- Internal: Research Incentive Grant, Creighton University College of Arts & Sciences, “Determination of Key Structural Features of a Mammalian Riboswitch in Order to Design Novel Anti-Cancer Agents”
- CURAS Faculty Research Fund, “Antibiotic Properties of Artificial Agonists for a Bacterial Riboswitch”
Awards and Honors
- INBRE Scholars Program, National Institutes of Health, 2016
- INBRE Scholars Program, National Institutes of Health, 2016
- Summer Internship Program in Biomedical Research (SIP), National Institutes of Health, 2016
- Ferlic Summer Research Fellowship, CURAS, 2016
- Maiben lecture invited speaker, Nebraska Academy of Sciences, 2016
- Invited Speaker, 2016
- Council on Undergraduate Research Councilor, Elected by Council on Undergradiate Research, 2016
- Invited Speaker, 2015
- Chosen for SciMix Poster Presentation, American Chemical Society, 2015
- Ferlic Summer Research Fellowship, CURAS, 2015
- Summer Undergraduate Research Program, Mayo Clinic, 2015
- INBRE Scholars Program, National Institutes of Health, 2015
- Invited Speaker, 2015
- Invited Speaker, 2015
- Invited Speaker, 2015
- Summer Research Fellowship, Creighton Honors Program, 2014
- INBRE Scholars Program, National Institutes of Health, 2014
- Ferlic Summer Research Fellowship, CURAS, 2014
- Nominee for Undergraduate Research Fellows Award, 2014
- Soukup, J.K., Soukup, G.A. “Examination of spermine riboswitch function from different organisms for the development of antibiological agents”, Filed September 20, 2013, 61/880,553, 2013
- Gordon Research Conference PUI Travel Award, 2013
- INBRE Scholars Program, National Institutes of Health, 2013
- INBRE Scholars Program, National Institutes of Health, 2013
- Best Oral Presentation, 38th West Coast Biological Sciences Undergraduate Research Conference, 2013
- Best Undergraduate Poster, St. Albert's Day Research Symposium, 2013
- Honorary Inductee, Creighton University Alpha SIgma Nu (Jesuit Honor Society), 2013
- College Award for Professional Excellence in Major Advising, Creighton College of Arts & Sciences, 2013
- Award Winner, Gordon Research Conference, 2013
- Ferlic Summer Research Fellowship, College of Arts & Sciences, 2012
- Ferlic Summer Research Fellowship, College of Arts & Sciences, 2012
- INBRE Scholars Program, National Institutes of Health, 2012
- INBRE Scholars Program, National Institutes of Health, 2012
- Outstanding Undergraduate Research in Biological Sciences, Nebraska Academy of Sciences, 2012
- Creighton University Research Award, 2012
- Richard Holland Future Scientist Award, Nebraska IDeA Networks of Biomedical Research Excellence Meeting, 2011
- INBRE Scholars Program, National Institutes of Health, 2011
- INBRE Scholars Program, National Institutes of Health, 2011
- INBRE Scholars Program, National Institutes of Health, 2011
- Ferlic Summer Research Fellowship, College of Arts & Sciences, 2011
- Contributor, Luce Foundation, 2011
- INBRE Scholars Program, National Institutes of Health, 2010
- INBRE Scholars Program, National Institutes of Health, 2010
- Richard Holland Future Scientist Award, 2010
- Ferlic Summer Research Fellowship, College of Arts & Sciences, 2010
- Ferlic Summer Research Fellowship, College of Arts & Sciences, 2010
- INBRE Scholars Program, National Institutes of Health, 2010
- Chosen for SciMix Poster Presentation, American Chemical Society, 2010
- Nominee for Creighton University Research Award, 2010
- Creighton Representative, 2010
- Nominee for Carnegie Foundation U.S. Professors of the Year award, 2009
- Soukup, G.A., Soukup, J.K. “GlmS ribozyme coenzymes and methods of use thereof,” International Patent Cooperation Treaty Application PCT/US 2006/21965, 2006