Carol A. Fassbinder-Orth, PhD
Carol A. Fassbinder-Orth, PhD

Carol A. Fassbinder-Orth, PhD

Professor
Director, Center for Undergraduate Research and Scholarship
Director, Center for Undergraduate Research and Scholarship
College of Arts and Sciences

Academic Appointments

Department

  • Biology

Position

  • Professor

Teaching Activity

  • BIO 201: General Biology
  • BIO 449: Animal Physiology
  • BIO 450: Animal Physiology Lab
  • BIO 451: Microbiology
  • BIO 539: Ecology of Zoonotic Diseases

Biography

Carol Fassbinder-Orth received her BS from Iowa State University in Genetics in 2003 and her PhD in Zoology from the University of Wisconsin-Madison in 2008. Dr. Fassbinder-Orth has been a faculty member in the Biology Department at Creighton University in Omaha, NE since 2008. Her areas of teaching expertise include microbiology, disease ecology, and physiology. Her general research foci are ecoimmunology and disease ecology, with specific interests in honey bee disease dynamics.

Publications and Presentations

Articles

  • Orth, A.J., E. H. Curran, E.J. Haas, A. C. Kraemer, A.M. Anderson, N. J. Mason, C. A. Fassbinder-Orth. 2021. Land use influences the composition and antimicrobial effects of propolis. Submitted to: Journal of Apicultural Research., Journal of Apicultural Research, 2021
  • Fassbinder-Orth, C.A., L. D. Igl, D. C. Hahn, K. M. Watts, T. E. Wilcoxen, and K. R. Ramos-Álvarez. 2019. Do life history traits influence patterns of maternal immune elements in New World blackbirds (Icteridae)? Integrative Organismal Biology. 1(1):oby011. https://doi.org/10.1093/iob/oby011, Integrative Organismal Biology, 1, 2019
  • Blob, R.W., M.A. Butler, C.G. Farmer, C.A. Fassbinder-Orth, L.P. Hernandez, I.T. Moore, U.K. Muller, R.A. Satterlie, S.H. Williams, and A.P. Summers. 2019. Integrative Organismal BiologyA Journal We Want and Need. Integrative Organismal Biology. https://doi:10.1093/iob/oby005., Integrative Organismal Biology, 1, 2019

  • Fassbinder-Orth, C., T. Killpack, D. Goto, E. Rainwater, V. Shearn-Bochsler. 2018. High costs of infection: Alphavirus infection reduces digestive function and bone and feather growth in nestling birds. Submitted to PLoS ONE 13(4): e0195467. https://doi.org/10.1371/journal.pone.0195467
     , PLoS One, 13(4), e0195467, 2018
  • Fassbinder-Orth, C., T. Wilcoxen, T. Tran, R. Boughton, J. Fair, E. Hofmeister, J. Grindstaff, and J. Owen. 2016. Immunoglobulin detection in wild birds: effectiveness of three secondary anti-avian IgY antibodies in direct ELISAs in 41 avian species. Methods in Ecology and Evolution. 7:1174-1181., Methods in Ecology and Evolution, 7, 1174-1181, 2016
  • Hofmeister, E., R. Dusek, C. Fassbinder-Orth, B. Owen, and J.C. Franson. 2016. Susceptibility and antibody response of vesper sparrows (Pooecetes gramineus) to West Nile virus: A potential amplification host in sage-brush grassland habitat. Journal of Wildlife Diseases. 52: 345-353., Journal of Wildlife Diseases, 52, 345-353, 2016
  • Fassbinder-Orth, C. A. Methods for quantifying gene expression in ecoimmunology: from qPCR to RNA-Seq, Integrative and Comparative Biology, 54, 396-406, 2014
  • Fassbinder-Orth, Carol, Barak, Virginia A., Rainwater, Ellecia L., Altrichter, Ashley M. Buggy Creek Virus (Togaviridae: Alphavirus) Upregulates Expression of Pattern Recognition Receptors and Interferons in House Sparrows ( Passer domesticus), Vector Borne & Zoonotic Diseases, 14, 439-446, 2014
  • Meier, Samuel A., Fassbinder-Orth, Carol A., Karasov, William H. Ontogenetic changes in innate immune function in captive and wild subspecies of prairie-chickens ( Tympanuchus cupido spp.), Journal of Wildlife Management, 77, 633-638, 2013
  • Fassbinder-Orth, Carol A., Barak, Virginia A., Brown, Charles R. Immune Responses of a Native and an Invasive Bird to Buggy Creek Virus (Togaviridae: Alphavirus) and Its Arthropod Vector, the Swallow Bug (Oeciacus vicarius), PLoS One, 8, e58045, 2013
  • Fassbinder-Orth, C., Barak, V., Brown, C. Avian Immune Responses to Alphavirus Infections, Integrative and Comparative Biology, 52, E56-E56, 2012
  • Fassbinder-Orth, Carol A., Hofmeister, Erik K., Weeks-Levy, Carolyn, Karasov, William H. Oral and Parenteral Immunization of Chickens (Gallus gallus) Against West Nile Virus with Recombinant Envelope Protein, Avian Diseases, 53, 502-509, 2009

Editing and Reviews

  • Fassbinder-Orth, C. The avian migrant: the biology of bird migration, Choice: Current Reviews for Academic Libraries, 51, 867-867, 2014
  • Fassbinder-Orth, C. Penguins: natural history and conservation, Choice: Current Reviews for Academic Libraries, 51, 296-296, 2013

Presentations

  • Fassbinder-Orth, C. Effects of Arbovirus Infections on Digestive Physiology, Growth, and Survival in Young Animals. Invited Symposium at the Society for Integrative and Comparative Biology annual meeting, Austin, TX (January 3-7, 2020)., 2020
  • C. Fassbinder-Orth. Honey bees in peril: an investigation of colony collapse disorder and honey bee viral infection dynamics. Invited seminar at Kansas State University Division of Biological Sciences. (Oct. 21, 2019)., 2019
  • C. Fassbinder-Orth, S. Hughes, R. Sabotin, G. Push, and T. Tran. Honey bees in peril: The effects of a dicistrovirus infection on honey bee physiology, aging, and behavior. Oral presentation at the annual meeting for the American Society for Virology, Minneapolis, MN (July 20-24, 2019)., 2019
  • Rollman, T., T. Rowan, B. Ryan, and C. Fassbinder-Orth. Seasonal Population Dynamics of Swallow Bugs (Oeciacus vicarius) and their Endemic Alphavirus, Buggy Creek virus. Poster presentation at the annual meeting for the American Society for Virology, Minneapolis, MN (July 20-24, 2019)., 2019
  • Rollman, T., T. Rowan, B. Ryan, and C. Fassbinder-Orth. Buggy Creek virus Phenotype Dynamics in Swallow Bugs (Oeciacus vicarious). Poster presentation at the annual meeting for Missouri and Missouri Valley Branches of American Society of Microbiology Conference, Omaha, NE (March 15-16, 2019)., 2019
  • Fassbinder-Orth, C. S. Hughes, R. Sabotin, T. Tran, G. Push. Honey bees in peril: an investigation of honey bee viral infection dynamics. Oral presentation at the annual meeting of the Society for Integrative and Comparative Biology, Tampa, FL (January 3-7, 2019)., 2019
  • Hughes, S., and C. Fassbinder-Orth. Radio frequency identification as a tracking system: a study of honey bee behavior. Poster presentation at the annual meeting of the Society for Integrative and Comparative Biology, Tampa, FL (January 3-7, 2019), 2019
  • Fassbinder-Orth, C., R. Sabotin, and T. Tran. Honey Bees in Peril: The use of cricket paralysis virus as a model honey bee virus system to study colony collapse disorder. Oral presentation at the Society for Invertebrate Pathology Meeting in Gold Coast, Australia (August 6-12, 2018)., 2018
  • Sabotin, R., T. Tran, and C. Fassbinder-Orth. Vitellogenin Expression in Honey Bees (Apis mellifera): How viral infections influence honey bee physiology. Poster presentation at the annual meeting of the Society for Integrative and Comparative Biology, San Francisco, CA (January 3-7, 2018)., 2018
  • Fassbinder-Orth, C., and T. Tran. Honey Bee Viral Infections: Establishment of an Infection Model and Determination of the Effects of Varroa Mites on Viral Infection Severity. Poster presentation at the annual meeting for the Society for Integrative and Comparative Biology, New Orleans, LA (January 3-7, 2017)., 2017
  • Fassbinder-Orth, C., T. Rowan . Exploring the dynamics of Buggy Creek virus, a unique alphavirus in an insect-avian enzootic cycle. Oral presentation at the American Society for Virology annual meeting, Blacksburg, VA, (June 18, 2016)., 2016
  • Klostermeyer, K, C. Hahn, and C. Fassbinder-Orth. Comparison of total immunoglobulins in the albumen of avian brood parasites and non-brood parasites. Poster presentation at the annual meeting of the Society for Integrative and Comparative Biology, Portland, OR. (January 3, 2016)., 2016
  • Fassbinder-Orth, C., J. Katz, N. Chapman, S. Tracy. Defective interfering particles in Buggy Creek virus, a unique alphavirus. Poster presentation at the American Society for Virology meeting, London, Ontario (July 11-15, 2015)., 2015
  • Using molecular techniques to measure immune responses and infectious disease dynamics in non-model species. C. Fassbinder-Orth. Invited Symposium at: Society for Integrative and Comparative Biology Annual Meeting, Austin, TX., 2014
  • Lipid digestion and absorption are impaired during an alphavirus infection in nestling birds. D. Goto, E. Rainwater, and C. Fassbinder-Orth. Oral presentation at: Society for Integrative and Comparative Biology Annual Meeting, Austin, TX., 2014
  • Effects of an arbovirus infection on nestling house sparrow digestive enzyme activity. M. Walek, B. Kawamoto, R. Shrestha, T. Tran, and C. Fassbinder-Orth. Poster presentation at: Society for Integrative and Comparative Biology Annual Meeting, Austin, TX., 2014
  • Expanding our toolbox in avian ecological immunology: effectiveness of a new anti-passerine IgY detecting antibody in wild birds. T. Tran, R. Boughton, J. Fair, T. Wilcoxen, E. Hofmeister, and C. Fassbinder-Orth. Poster presentation at: Society for Integrative and Comparative Biology Annual Meeting, Austin, TX., 2014
  • Effects of an arbovirus infection on avian digestive enzyme activity. B. Kawamoto, M. Walek, R. Shrestha, T. Tran, and C. Fassbinder-Orth. Poster presentation at the Nebraska Physiological Society meeting in Omaha, NE., 2013
  • Alphavirus infection impairs growth and digestive function in nestling birds. D. Goto, E. Rainwater, T. Killpack, and C. Fassbinder-Orth. Invited oral presentation at the Nebraska Physiological Society meeting in Omaha, NE., 2013
  • Immune responses of a native and an invasive bird to an alphavirus and its arthropod vector. C. Fassbinder-Orth, V. Barak, and C. Brown. Poster presentation at: the National Science Foundation Research Coordination Network in Ecoimmunology meeting. Berlin, Germany., 2013
  • Avian Adaptive Immune Responses to Buggy Creek Virus (Togaviridae: Alphavirus) and its Arthropod Vector, the Swallow Bug (Oeciacus vicarius). V. Barak, C. Brown, C. Fassbinder-Orth. Oral presentation at: Nebraska Academy of Sciences, Lincoln, NE., 2013
  • Experimental inoculation of nestling houses sparrows (Passer domesticus) with Buggy Creek virus. E. Rainwater, C. Fassbinder-Orth. Oral presentation at: Nebraska Academy of Sciences, Lincoln, NE., 2013
  • Avian Adaptive Immune Responses to Buggy Creek Virus (Togaviridae: Alphavirus) and its Arthropod Vector, the Swallow Bug (Oeciacus vicarius). V. Barak, C. Brown, C. Fassbinder-Orth. Oral presentation at: Society for Integrative and Comparative Biology Annual Meeting, San Francisco, CA., 2013
  • Experimental inoculation of nestling houses sparrows (Passer domesticus) with Buggy Creek virus. E. Rainwater, C. Fassbinder-Orth. Oral presentation at: Society for Integrative and Comparative Biology Annual Meeting, San Francisco, CA., 2013
  • Alphavirus infection impairs growth and development of altricial nestling birds. M. Hiatt, Tess Killpack, W. Crouch, C. Fassbinder-Orth. Poster presentation at: Society for Integrative and Comparative Biology Annual Meeting, San Francisco, CA., 2013
  • Avian Alphavirus Infections: Studying the Immune Response with Bead-Based Gene Expression Assays. C.A. Fassbinder-Orth, V. Barak, and C. Brown. Poster presented at the NSF Research Coordination Network in Ecoimmunology Conference, Ann Arbor, MI., 2012
  • C. A. Fassbinder-Orth, V. Barak, and C. Brown. 2012. Avian Immune Responses to Alphavirus Infections. Oral presentation at: Society for Integrative and Comparative Biology Annual Meeting, Charleston, SC., 2012
  • Ashley Altrichter and C. A. Fassbinder-Orth. 2011. Comparative avian immunogenetics: an exploration of antiviral genes in several wild bird species. Poster presented at: Society for Integrative and Comparative Biology Annual Meeting, Salt Lake City, UT., 2011

Research and Scholarship

Research and Scholarship Interests

  • Virology, Ecoimmunology, Zoonotic diseases

Current Research Projects

  • 1. Development of an immortal honeybee cell line
    2. Physiological markers of aging in honeybees
    3. Effects of pesticides on honeybee behavior

Grant Funding Received

  • Exploration of Quasispecies Dynamics in an Alphavirus. C.A. Fassbinder-Orth. Submitted to Creighton’s Summer Faculty Research Fund
  • An investigation of Buggy Creek virus replication dynamics. C.A. Fassbinder-Orth. Submitted to Creighton’s CURAS Faculty Research Fund
  • Effects of Buggy Creek Virus Infection on Avian Bone Development. C.A. Fassbinder-Orth, Mohammed Akhter, James Platz. Submitted to Creighton’s Dr. George F. Haddix President’s Faculty Research fund
  • Avian Immune Responses to Ectoparasites and Alphaviruses. Submitted to Creighton College of Arts and Sciences Research Incentive Award
  • INBRE: Dynamics of Buggy Creek virus infection: Investigations with in vitro and in vivo models. (C.A. Fassbinder-Orth. Submitted to: Nebraska INBRE program
  • NSF: Collaborative Research: EAGER: Establishing immortalized cell lines from the European honey bee, Apis mellifera

Awards and Honors

  • Creighton Summer Faculty Research Fellowship, Creighton University, 2011